Ro 31-9790


CAS No. : 145337-55-9

(Synonyms: GI4747)

145337-55-9
Price and Availability of CAS No. : 145337-55-9
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5mg $460 In-stock
10mg $735 In-stock
25mg $1360 In-stock
50mg $2180 In-stock
100mg $3500 In-stock
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Cat. No. : HY-101703
M.Wt: 315.41
Formula: C15H29N3O4
Purity: >98 %
Solubility: DMSO : 50 mg/mL (ultrasonic;warming;heat to 70°C)
Introduction of 145337-55-9 :

Ro 31-9790 is a synthetic metalloproteinase (MMP) inhibitor. IC50 & Target:MMP[1] In Vitro: Ro 31-9790 inhibits L-selectin shedding from mouse and human lymphocytes, Jurkat T cells, and human monocytes with an IC50 of 0.3-0.4 μM on these cell types. The IC50 values obtained for Ro 31-9790 are 4.82 ± 0.75 μM, 1.16 ± 0.27 μM, 0.70 ± 0.06 μM, 4.47± 1.27 μM and 0.38 ± 0.05 μM for mouse lymphocyte L-selectin shedding, Jurkat L-selectin shedding, human lymphocyte L-selectin shedding, human monocyte L-selectin shedding and human monocyte TNF-α shedding[1].

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