A-77636 (hydrochloride)


CAS No. : 145307-34-2

145307-34-2
Price and Availability of CAS No. : 145307-34-2
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Cat. No. : HY-103416
M.Wt: 365.89
Formula: C20H28ClNO3
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 145307-34-2 :

A-77636 hydrochloride is a potent, orally active, selective and long acting dopamine D1 receptor agonist (pKi=7.40; Ki=39.8 nM) with antiparkinsonian activity. A-77636 hydrochloride is functionally inactive at dopamine D2 receptor[1][2]. In Vivo: A-77636 (0.1-1 mg/kg) exerts a suppressant effect on food intake, due principally to a reduction in meal size and duration[3].

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