DB772


CAS No. : 1451058-50-6

1451058-50-6
Price and Availability of CAS No. : 1451058-50-6
Size Price Stock
5mg $350 In-stock
10mg $600 In-stock
25mg $1250 In-stock
50mg $1950 In-stock
100 mg Get quote
200 mg Get quote
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Cat. No. : HY-114621
M.Wt: 401.29
Formula: C20H18Cl2N4O
Purity: >98 %
Solubility: DMSO : 10 mg/mL (ultrasonic)
Introduction of 1451058-50-6 :

DB772 hydrate is a bovine viral diarrhoea virus (BVDV) inhibitor. DB772 also has anti-prion activity[1]. In Vitro: DB772 hydrate (0-100 μM, 96 hours) can inhibit replication of the viruses BVDV2 and BDV at concentrations greater than 0.2 μM, Bungowannah virus replication at concentrations greater than 0.01 μM, and HoBi virus replication greater than 1.65 μM[2].
DB772 hydrate has antiprion activity with CC50 (50% cytotoxic concentration) value of 3.8 μM, TC-EC50 (50% tissue culture effective concentration) value of 0. 8 μM and inhibits PrPSc accumulation in sheep microglia[3].

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