HDAC3-IN-T247
CAS No. : 1451042-18-4
| Size | Price | Stock |
|---|---|---|
| 5mg | $250 | In-stock |
| 10mg | $400 | In-stock |
| 25mg | $850 | In-stock |
| 50mg | $1350 | In-stock |
| 100mg | $1950 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-123295 |
| M.Wt: | 389.47 |
| Formula: | C21H19N5OS |
| Purity: | >98 % |
| Solubility: | DMSO : 25 mg/mL (ultrasonic) |
HDAC3-IN-T247 is a potent and selective HDAC3 (histone deacetylase 3) inhibitor, with an IC50 of 0.24 µM. HDAC3-IN-T247 induces a selective increase of NF-κB acetylation in HCT116 cells. HDAC3-IN-T247 shows anticancer and antiviral activity. HDAC3-IN-T247 inhibits growth of cancer cells, and activates HIV gene expression in latent HIV-infected cells[1]. IC50 & Target: IC50:0.24 μM (HDAC3), 19 μM (HDAC1)[1]
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