SLR080811
CAS No. : 1449765-65-4
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| Cat. No. : | HY-12896 |
| M.Wt: | 369.50 |
| Formula: | C21H31N5O |
| Purity: | >98 % |
| Solubility: |
SLR080811 is a guanidine-based selective sphingosine kinase 2 (SphK2) inhibitor with a Ki of 1.3 μM, exhibiting ~10-fold selectivity over SphK1 (Ki = 12 μM). SLR080811 reduces sphingosine 1-phosphate (S1P) levels in vitro, but drives a SphK1-dependent increase in S1P in mice. SLR080811 can be used for cancers and fibrosis research[1].
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