RS 09
CAS No. : 1449566-36-2
| Size | Price | Stock |
|---|---|---|
| 1mg | $50 | In-stock |
| 5mg | $120 | In-stock |
| 10mg | $190 | In-stock |
| 25mg | $350 | In-stock |
| 50 mg | Get quote | |
| 100 mg | Get quote | |
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| Cat. No. : | HY-P1439 |
| M.Wt: | 691.78 |
| Formula: | C31H49N9O9 |
| Purity: | >98 % |
| Solubility: | H2O : 100 mg/mL (ultrasonic) |
RS 09 is an LPS (HY-D1056) peptide mimic and TLR4 agonist. RS 09 can bind to TLR-4 and activate NF-κB. RS 09 can function as an adjuvant in vivo, enhancing the antigen-specific immune response[1].
In Vitro: RS 09 (1-10 μg/mL; 24 h) can stimulate TLR-4 and activate NF-κB in HEK-BLUETM-4 cells[1].
RS 09 (5 μg/mL; 15 min-24 h) can bind to TLR-4 and induce nuclear translocation of NF-κB as well as the secretion of inflammatory cytokines in RAW264.7 cells[1].
In Vivo: RS 09 is used as an adjuvant to co-immunize BALB/c mice with the prostate-cancer-specific antigen X-15 (conjugated to KLH). The results showed that RS 09 can significantly increase the concentration of X-15-specific antibodies in mice[1].
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