Resiquimod (GMP)
CAS No. : 144875-48-9
(Synonyms: R848 (GMP); S28463 (GMP))
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| Cat. No. : | HY-13740G |
| M.Wt: | 314.38 |
| Formula: | C17H22N4O2 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Resiquimod (R848) (GMP) is Resiquimod (HY-13740) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. Resiquimod is a Toll-like receptor 7 and 8 (TLR7/TLR8) agonist. Resiquimod (GMP) can induce human mMDSC to mature into inflammatory macrophages[1][2][3].
In Vitro: Resiquimod (GMP) (3 µg/mL, 5 days) induces human mMDSC to mature into inflammatory macrophage (MACinflam)[1].
Resiquimod (GMP) (3 µg/mL, 3 days) produces IL-6 and IL-12 in human mMDSC[1].
Resiquimod (GMP) (2.5 µg/mL, 7 days) transdifferentiaes memory B cells to IgG producing plasma cells[2].
Resiquimod (GMP) (5 µg/mL, 5 days) induces the differentiation of MDSCs into mature myeloid cells[3].
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