Futibatinib
CAS No. : 1448169-71-8
(Synonyms: TAS-120)
| Size | Price | Stock |
|---|---|---|
| 1mg | $60 | In-stock |
| 5mg | $150 | In-stock |
| 10mg | $220 | In-stock |
| 25mg | $420 | In-stock |
| 50mg | $650 | In-stock |
| 100mg | $980 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
or Fax: (86)21-58955996
Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-100818 |
| M.Wt: | 418.45 |
| Formula: | C22H22N6O3 |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 29 mg/mL |
Futibatinib (TAS-120) is an orally bioavailable, highly selective, and irreversible FGFR inhibitor, with IC50s of 3.9, 1.3, 1.6, and 8.3 nM for FGFR 1-4, respectively. Futibatinib inhibits mutant and wild-type FGFR2 with similar IC50s (wild-type FGFR2=0.9 nM; V5651=1-3 nM; N550H=3.6 nM; E566G=2.4 nM)[1][2][3]. In Vitro:Futibatinib (TAS-120) covalently binds to a highly conserved P-loop cysteine residue in the ATP pocket of FGFR[1]. In Vivo:Futibatinib (TAS-120) (3, 30, 100 mg/kg/day, p.o.) exerts an anti-tumor effect in mice. Futibatinib (TAS-120) shows anti-tumor effect by administering at moderate intervals, such as intermittent administration of every other day dosing and 2 times/week, and reducing the sustained elevation and weight suppression blood phosphorus level, and take a antitumor effective as daily administration[1].
Lorem ipsum dolor sit amet, consectetur adipisicing elit. Autem earum hic iste maiores, nam neque rem suscipit. Adipisci consequatur error exercitationem fugit ipsam optio qui, quibusdam repellendus sed vero! Debitis.
Inquiry Information- Product Name:
- Futibatinib
- Cat. No.:
- HY-100818
- Quantity:
Your information is safe with us.