4F 4PP (oxalate)


CAS No. : 144734-36-1

144734-36-1
Price and Availability of CAS No. : 144734-36-1
Size Price Stock
5mg $80 In-stock
10mg $150 In-stock
50mg $450 In-stock
100mg $750 In-stock
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Cat. No. : HY-100970
M.Wt: 429.48
Formula: C24H28FNO5
Purity: >98 %
Solubility: DMSO : 12.5 mg/mL (ultrasonic;warming;heat to 60°C)
Introduction of 144734-36-1 :

4F 4PP (oxalate) is a selective 5-HT2A antagonist with almost as high affinity (Ki= 5.3 nM) as ketanserin but with a much lower affinity for 5-HT2C sites (Ki= 620 nM)[1][2][3][4]. IC50 & Target: Ki: 5.3 nM (5-HT2A), Ki: 620 nM (5-HT2C)[2][3][4] In Vivo: 4F 4PP (100 nM) reduces the lowest [D-ala2,N-me-phe4,gly.l5]-enkephalin (DAMGO) concentration and can produce a significant depression of evoked field potentials[1].

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