Mivebresib


CAS No. : 1445993-26-9

(Synonyms: ABBV-075)

1445993-26-9
Price and Availability of CAS No. : 1445993-26-9
Size Price Stock
2mg $96 In-stock
5mg $120 In-stock
10mg $180 In-stock
25mg $300 In-stock
50mg $540 In-stock
100mg $900 In-stock
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Cat. No. : HY-100015
M.Wt: 459.47
Formula: C22H19F2N3O4S
Purity: >98 %
Storage: at 20℃ 2 years
Solubility: DMSO : ≥ 37 mg/mL (80.53 mM)
Introduction of 1445993-26-9 :

Mivebresib is a potent and orally available bromodomain and extraterminal domain (BET) bromodomain inhibitor. Mivebresib binds to BRD4 with a Ki of 1.5 nM. IC50 & Target: IC50: 1.5 nM (BET)[1] In Vitro: Mivebresib inhibit DHT-stimulated transcription of AR target genes without significant effect on AR protein expression. In addition to blocking the transcription activation downstream of AR, Mivebresib is also a potent inhibitor of MYC and the TMPRSS2-ETS fusion proteins[1].

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