CAS No. : 1445993-26-9

(Synonyms: ABBV-075)

Price and Availability of CAS No. : 1445993-26-9
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Cat. No. : HY-100015
M.Wt: 459.47
Formula: C22H19F2N3O4S
Purity: >98 %
Storage: at 20℃ 2 years
Solubility: DMSO: ≥ 37 mg/mL
Introduction of 1445993-26-9 :

Mivebresib, a novel BET family inhibitor, disrupts critical transcription programs that drive prostate cancer growth to induce potent anti-tumor activity in vitro and in vivo. Also a potent inhibitor of MYC and the TMPRSS2-ETS fusion proteins. In Vitro: Mivebresib inhibit DHT-stimulated transcription of AR target genes without significant effect on AR protein expression. In addition to blocking the transcription activation downstream of AR, Mivebresib is also a potent inhibitor of MYC and the TMPRSS2-ETS fusion proteins[1].

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