Landiolol (hydrochloride) (Standard)
CAS No. : 144481-98-1
(Synonyms: ONO1101 (hydrochloride) (Standard))
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| Cat. No. : | HY-100607AR |
| M.Wt: | 546.05 |
| Formula: | C25H40ClN3O8 |
| Purity: | >98 % |
| Solubility: |
Landiolol (ONO1101) hydrochloride (Standard) is the analytical standard of Landiolol hydrochloride (HY-100607A). This product is intended for research and analytical applications. Landiolol (ONO1101) hydrochloride is a highly selective, ultra-short-acting competitive inhibitor of β1 adrenergic receptors. Landiolol hydrochloride specifically blocks cardiac β1 receptors, reducing heart rate and myocardial oxygen consumption. Landiolol hydrochloride inhibits TNF-α-induced excessive mitochondrial oxygen consumption and reactive oxygen species production in a sepsis model, alleviating renal injury. Landiolol hydrochloride has little effect on cardiac ion channels (such as L-type calcium current and inward rectifier potassium current) and has a weak negative inotropic effect. Landiolol hydrochloride can be used for perioperative tachycardia control and protection studies of sepsis-related acute kidney injury[1][2][3]. IC50 & Target:beta-adrenergic receptor[1]
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