GDC-0927 (Racemate)


CAS No. : 1443983-36-5

(Synonyms: SRN-927 (Racemate))

1443983-36-5
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Cat. No. : HY-111484A
M.Wt: 461.52
Formula: C28H28FNO4
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 1443983-36-5 :

GDC-0927 Racemate (SRN-927 Racemate) is a degrader of estrogen receptor, potently inhibits ER-α activity, with an IC50 of 0.2 nM, and is used in the research of ER-related diseases. IC50 & Target: IC50: 0.2 nM (ER-α)[1] In Vitro: GDC-0927 Racemate (Example 1) is a degrader of estrogen receptor, potently inhibits ER-α activity, with an IC50 of 0.2 nM, and is used in the research of ER-related diseases. GDC-0927 Racemate reduces the viability of MCF7 cells with an IC50 of 0.21 nM[1].

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