ML337


CAS No. : 1443118-44-2

1443118-44-2
Price and Availability of CAS No. : 1443118-44-2
Size Price Stock
5mg $130 In-stock
10mg $210 In-stock
25mg $440 In-stock
50mg $750 In-stock
100mg $1250 In-stock
200 mg Get quote
500 mg Get quote
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Cat. No. : HY-16636
M.Wt: 353.39
Formula: C21H20FNO3
Purity: >98 %
Solubility: DMSO : 125 mg/mL (ultrasonic)
Introduction of 1443118-44-2 :

ML337 is a selective and brain-penetrant negative allosteric modulator of mGlu3, with an IC50 of 593 nM. ML337 possesses a favorable dystrophia myotonica protein kinase (DMPK) and ancillary pharmacology profile[1]. ML337 is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. IC50 & Target:IC50: 593 nM (mGlu3)[1] In Vitro: ML337 has no activity at mGlu1, 2, 4, 5, 6, 7 and 8 at concentrations up to 30 μM[1].

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