β-Amyloid (22-35)
CAS No. : 144189-71-9
(Synonyms: Amyloid β-Protein (22-35))
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| Cat. No. : | HY-P1474 |
| M.Wt: | 1403.62 |
| Formula: | C59H102N16O21S |
| Purity: | >98 % |
| Solubility: | H2O : 1.82 mg/mL (ultrasonic;adjust pH to 3 with HCl);DMSO : 1.85 mg/mL (ultrasonic;adjust pH to 5 with HCl) |
β-Amyloid 22-35 (Amyloid β-Protein 22-35), the residues 22-35 fragment ofβ-amyloid protein, has a cytotoxic effect on cultured neurons from the rat hippocampus in serum-free medium. β-Amyloid 22-35 forms aggregates and typical amyloid fibrils resembling those of the β-amyloid protein in neutral buffer solution)[1]. IC50 & Target: Amyloid-β[1] In Vitro: β-Amyloid 22-35 shows significant cytotoxicity on the rat hippocampal neurons at 40 μg/mL, but exhibits no cytotoxic effect on the glial cells[1].
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