2',3'-cGAMP
CAS No. : 1441190-66-4
(Synonyms: 2'-3'-cyclic GMP-AMP)
| Size | Price | Stock |
|---|---|---|
| 1mg | $300 | In-stock |
| 5mg | $690 | In-stock |
| 10mg | $1250 | In-stock |
| 25mg | $2500 | In-stock |
| 50mg | $4000 | In-stock |
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| Cat. No. : | HY-100564 |
| M.Wt: | 674.41 |
| Formula: | C20H24N10O13P2 |
| Purity: | >98 % |
| Solubility: | H2O : ≥ 50 mg/mL |
2',3'-cGAMP (2'-3'-cyclic GMP-AMP) is a endogenous cGAMP in mammalian cells. 2',3'-cGAMP binds to STING with a high affinity and is a potent inducer of interferon-β (IFNβ). 2',3'-cGAMP is produced in mammalian cells in response to DNA in the cytoplasm[1]. IC50 & Target:STING, IFNβ[1] In Vitro: 2',3'-cGAMP (2'-3'-cyclic GMP-AMP) contains two distinct phosphodiester linkages, one between 2′-OH of GMP and 5′-phosphate of AMP, and the other between 3′-OH of AMP and 5′-phosphate of GMP[1].
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