T-1101
CAS No. : 1438638-83-5
(Synonyms: TAI-95)
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| Cat. No. : | HY-120356 |
| M.Wt: | 493.60 |
| Formula: | C24H23N5O3S2 |
| Purity: | >98 % |
| Solubility: |
T-1101 (TAI-95) is an orally active inhibitor for mitose regulating highly expressed oncoprotein 1 (Hec1). T-1101 blocks the interaction between Hec1 and NEK2, exhibits cytotoxicity in human liver cancer cells with GI50 of 15-70 nM. T-1101 induces apoptosis in Huh-7. T-1101 exhibits antitumor efficacy in mouse models[1].
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