Chromafenozide


CAS No. : 143807-66-3

(Synonyms: ANS118)

143807-66-3
Price and Availability of CAS No. : 143807-66-3
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Cat. No. : HY-17533
M.Wt: 394.51
Formula: C24H30N2O3
Purity: >98 %
Solubility: DMSO : 250 mg/mL (ultrasonic)
Introduction of 143807-66-3 :

Chromafenozide is a potent partial ecdysone receptor agonist and dibenzoylhydrazine insecticide. Chromafenozide inhibits insect feeding and causes the insect to molt prematurely, leading to death. Chromafenozide shows antagonistic activity against 20-HE. Chromafenozide shows high toxicity against Spodoptera exigua and Spodoptera littoralis[1][2][3][4][5]. In Vitro:Chromafenozide (0.01-0.1 nM) reduces the luciferase activity induced by 20-HE by about half in Sf9 cells, showing antagonistic activity against 20-HE[1].
Chromfenoxate (0.1 nM-100 μM; 5 days) inhibits proliferation of both Se4 and S2 cells, with higher inhibitory activity against Se4 cells than against S2 cells[2].
In Vivo:Chromafenozide (0.39-39.4 ng/larva; topical application; 7 days) shows high toxicity against Spodoptera exigua and Spodoptera littoralis[2].

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