LDN193189 (dihydrochloride) (Standard)


CAS No. : 1435934-00-1

(Synonyms: DM-3189 (dihydrochloride) (Standard))

1435934-00-1
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Cat. No. : HY-12071BR
M.Wt: 479.40
Formula: C25H24Cl2N6
Purity: >98 %
Solubility:
Introduction of 1435934-00-1 :

LDN-193189 (dihydrochloride) (Standard) is the analytical standard of LDN-193189 (dihydrochloride). This product is intended for research and analytical applications. LDN-193189 (dihydrochloride) is a potent selective BMP type I receptor (BMP I) inhibitor. LDN-193189 efficiently inhibits transcriptional activity of the BMP type I receptors ALK2 and ALK3 with IC50 values of 5 nM and 30 nM, respectively. LDN-193189 can be used for the research of bone morphogenetic protein signalling, such as fibrodysplasia ossificans progressiva[1][2][3].

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