Bay-X-7195
CAS No. : 143538-27-6
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| Cat. No. : | HY-19161 |
| M.Wt: | 520.64 |
| Formula: | C30H32O6S |
| Purity: | >98 % |
| Solubility: |
Bay-X-7195 is a CYS leukotriene 1 receptor (CYS LT1) antagonist. Bay-X-7195 shows an antagonistic action to LTD4-induced bronchoconstriction in vitro and in vivo. Bay-X-7195 can be used foe the study of allergic and asthmatic[1][2].
In Vitro:In in vitro experiments, Bay-X-7195 inhibits LTD4-induced contraction of isolated guinea pig tracheal muscle (pA2 = 8.03)[2].
In Vivo:Bay-X-7195 at doses of 3-30 mg/kg clearly inhibits LTD4-induced increases in respiratory resistance (Rrs) in guinea pigs[2].
In mice, aeroantigen-induced airway inflammation are clearly inhibited by Bay-X-7195[3].
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