Eltoprazine (dihydrochloride)
CAS No. : 143485-51-2
(Synonyms: DU 28853 (dihydrochloride))
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| Cat. No. : | HY-16687B |
| M.Wt: | 293.19 |
| Formula: | C12H18Cl2N2O2 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Eltoprazine (DU 28853) dihydrochloride is a 5-HT1A/5-HT1B receptors agonist and a 5-HT2C receptor antagonist. Eltoprazine dihydrochloride shows antiaggressive and anxiogenic effects[1][2]. In Vivo:Rats are chronically treated with Mianserin (10 mg/kg i.p.) or Eltoprazine (1 mg/kg i.p.) and are tested in the elevated plus-maze test for anxiety. Mianserin and Eltoprazine display opposite effects in the elevated plus-maze: Mianserin induces anxiolytic-like effects, while Eltoprazine shows anxiogenic-like ones[2].
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