Naratriptan (hydrochloride) (Standard)
CAS No. : 143388-64-1
(Synonyms: GR-85548A hydrochloride (Standard))
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| Cat. No. : | HY-B0197AR |
| M.Wt: | 371.93 |
| Formula: | C17H26ClN3O2S |
| Purity: | >98 % |
| Solubility: |
Naratriptan (GR-85548A) hydrochloride (Standard) is the analytical standard of Naratriptan hydrochloride (HY-B0197A). This product is intended for research and analytical applications. Naratriptan is a selective 5-HT1B/1D receptor agonist. Naratriptan is peripherally active and has good oral bioavailability, inducing cranial artery vasoconstriction by activating 5-HT1B/1D receptors (EC50=0.11 μM for dog basilar artery). Naratriptan also inhibits trigeminal nerve-mediated dural neurogenic plasma extravasation and reduces sterile inflammation. Naratriptan is mainly used in the research of acute migraine, targeting cranial vascular and neuroinflammatory mechanisms[1][2][3][4].
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