LY2955303
CAS No. : 1433497-19-8
| Size | Price | Stock |
|---|---|---|
| 5mg | $100 | In-stock |
| 10mg | $160 | In-stock |
| 25mg | $370 | In-stock |
| 50mg | $600 | In-stock |
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| 200 mg | Get quote | |
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| Cat. No. : | HY-107765 |
| M.Wt: | 578.74 |
| Formula: | C36H42N4O3 |
| Purity: | >98 % |
| Solubility: | DMSO : 30 mg/mL (ultrasonic;warming) |
LY2955303 is a potent and selective retinoic acid receptor gamma (RARγ) antagonist with a Ki of 1.09 nM. IC50 & Target: Ki: 1.09 nM (RARγ)[1] In Vitro: LY2955303 is tested and observed that the binding Kis for RARα, RARβ and RARγ are >1700, >2980 and 1.09 nM, respectively. The functional Ki for RARγ is 7.1±4.9 nM[1]. In Vivo: A single oral dose of LY2955303 demonstrates a dose responsive effect whereby the rat reduces differential weight bearing (ED50=0.72 mg/kg)[1].
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