Eletriptan


CAS No. : 143322-58-1

(Synonyms: UK-116044)

143322-58-1
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Cat. No. : HY-A0039
M.Wt: 382.52
Formula: C22H26N2O2S
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 143322-58-1 :

Eletriptan (UK-116044) is a highly selective and orally active serotonin 5-HT1B and 5-HT1D receptor agonist, with pKi values of 8.0 and 8.9, respectively. Eletriptan has inhibitory effects on markers of neurogenic inflammation in rats. Eletriptan can be used for researching migraine[1]. In Vivo: Eletriptan (10, 30, 100, 300 and 1000 µg/kg; i.v.) reduces total carotid blood flow in anaesthetised pigs by selectively reducing carotid arteriovenous anastomotic blood flow and increasing nutrient blood flow within the carotid vascular bed[2].

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