Sameridine
CAS No. : 143257-97-0
(Synonyms: NIH 10908 (free base))
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| Cat. No. : | HY-105525 |
| M.Wt: | 330.51 |
| Formula: | C21H34N2O |
| Purity: | >98 % |
| Solubility: |
Sameridine (NIH-10908 free base) is a weak partial agonist of the μ-opioid receptor. Sameridine shows local anesthetic and analgesic properties. Sameridine has minimal respiratory depression at low doses, but can suppress ventilatory response at high doses. Sameridine can be used for the study of analgesic effect[1][2]. In Vivo:Sameridine (5-10 mg/mL, intrathecal injection, twice daily, five days a week, for two weeks) did not induce significant neurotoxicity in a rat model after intrathecal injection[3].
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