Tin protoporphyrin IX dichloride
CAS No. : 14325-05-4
(Synonyms: Tin-protoporphyrin IX; Sn-Protoporphyrin; SnPPIX)
| Size | Price | Stock |
|---|---|---|
| 5mg | $130 | In-stock |
| 10mg | $210 | In-stock |
| 25mg | $360 | In-stock |
| 50mg | $520 | In-stock |
| 100mg | $755 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
or Fax: (86)21-58955996
Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-101194 |
| M.Wt: | 750.26 |
| Formula: | C34H32Cl2N4O4Sn |
| Purity: | >98 % |
| Solubility: | DMF : 1 mg/mL (ultrasonic;warming);DMSO : 0.5 mg/mL (ultrasonic;warming);1M NaOH : 5 mg/mL (ultrasonic);0.1 M NaOH : 12.5 mg/mL (ultrasonic) |
Tin protoporphyrin IX dichloride (SnPPIX) is a potent Heme oxygenase-1 (HO-1) inhibitor. Tin protoporphyrin IX dichloride sensitizes pancreatic ductal adenocarcinoma (PDAC) tumors to chemotherapy in mice model[1]. IC50 & Target:IC50: Heme oxygenase-1 (HO-1)[1] In Vitro:Tin protoporphyrin IX dichloride (20 μM, 50 μM; 24 hours) significantly suppressed the proliferation of Capan-1 and CD18/HPAF cells. In contrast, Tin protoporphyrin IX dichloride has no significant effect on PDAC cells proliferation at all exposures except at 50 μM[1]. In Vivo:Tin protoporphyrin IX dichloride (intraperitoneal injection; 5 mg/kg; at 0, 7, 15, and 20 days) alone or combines with Gemcitabine significantly reduced the weight of pancreatic tumors (P < 0.05), decreases metastasis and improved the efficacy of Gemcitabine treatment[1].
Lorem ipsum dolor sit amet, consectetur adipisicing elit. Autem earum hic iste maiores, nam neque rem suscipit. Adipisci consequatur error exercitationem fugit ipsam optio qui, quibusdam repellendus sed vero! Debitis.
Inquiry Information- Product Name:
- Tin protoporphyrin IX dichloride
- Cat. No.:
- HY-101194
- Quantity:
Your information is safe with us.