Sinitrodil


CAS No. : 143248-63-9

(Synonyms: ITF 296)

143248-63-9
Price and Availability of CAS No. : 143248-63-9
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Cat. No. : HY-106914
M.Wt: 238.20
Formula: C10H10N2O5
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 143248-63-9 :

Sinitrodil (ITF 296) is an orally active organic nitrate with anti-ischaemic effect. Sinitrodil can be used for acute and chronic heart diseases research[1][2]. In Vivo: 1.19
Pharmacokinetic parameters of Sinitrodil in rats[2]
Route Parameter Value
IV (1 mg/kg) CL (L/h/kg) 2.7
AUC (μg h/mL) 0.37
T1/2 (h) 3.85
PO (5 mg/kg) Tmax (h) 0.17
T1/2 (h) 1.95
Cmax (μg/mL) 2.099
CL (L/h/kg) 2.69
AUC (μg h/mL) 1.364

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