Zinc phthalocyanine


CAS No. : 14320-04-8

(Synonyms: ZnPc)

14320-04-8
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Cat. No. : HY-19204
M.Wt: 577.90
Formula: C32H16N8Zn
Purity: >98 %
Solubility: 10 mM in DMSO;10 mM in Ethanol;10 mM in H2O
Introduction of 14320-04-8 :

Zinc phthalocyanine (ZnPc) is commonly applied in industry (catalysts, photoconductors) and biomedical (photodynamic therapy, PDT). Zinc phthalocyanine can be used to photooxidise cyclohexane and is promising for research of solar-cell applications[1][2][3][4]. In Vitro:Zinc phthalocyanine (1-10 μM, 24 h) inhibits the growth of cancer cell Kyse-140 and OE-33 with IC50 of 1.41 μM and 3.35 μM[3].
Zinc phthalocyanine (1-10 μM, 24 h) is a photosensitizer that can be taken up by cancer cells and produces ROS under light irradiation of a specific wavelength (694 nm), impaires mitochondrial membrane integrity, activates caspase-3, and induces apoptosis[3].
In Vivo:Zinc phthalocyanine (10 µM, topical application, single dose) causes long-term damage to the microvascular network of the CAM, exhibits antitumor activity in chick chorioallantoic membrane models[3].

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