WEHI-539
CAS No. : 1431866-33-9
| Size | Price | Stock |
|---|---|---|
| 1mg | $100 | Get quote |
| 5mg | $315 | Get quote |
| 10mg | $500 | Get quote |
| 50 mg | Get quote | |
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| Cat. No. : | HY-15607 |
| M.Wt: | 583.72 |
| Formula: | C31H29N5O3S2 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
WEHI-539 is a selective inhibitor of Bcl-XL with an IC50 of 1.1 nM. IC50 & Target: IC50: 1.1 nM (Bcl-XL)[1] In Vitro: WEHI-539 is a selective inhibitor of Bcl-XL. WEHI-539 augments Carboplatin induced caspase 3/7 activity, PARP cleavage and annexin V labelling. WEHI-539 as a single agent causes noticeable PARP cleavage in Ovcar-4 (5 μM in Ovcar-4.) and Ovsaho (1 μM in Ovsaho) cells[2].
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