KN-92 (hydrochloride)
CAS No. : 1431698-47-3
| Size | Price | Stock |
|---|---|---|
| 1mg | $40 | In-stock |
| 5mg | $130 | In-stock |
| 10mg | $220 | In-stock |
| 25mg | $370 | In-stock |
| 50mg | $550 | In-stock |
| 100mg | $780 | In-stock |
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| Cat. No. : | HY-15517B |
| M.Wt: | 493.45 |
| Formula: | C24H26Cl2N2O3S |
| Purity: | >98 % |
| Solubility: | H2O : 1 mg/mL (ultrasonic;warming;heat to 60°C);DMSO : ≥ 50 mg/mL |
KN-92 hydrochloride is an inactive derivative of KN-93, without CaM kinase inhibitory activity. KN-92 hydrochloride is intended to be used as a control compound in studies designed to elucidate the antagonist activities of KN-93[1][2].
In Vitro: KN-93 (5-50μM; 24 hours) inhibits LX-2 cell growth and KN-92 (5-50μM; 24 hours) is ineffective in blocking cell growth[2].
The analysis of cell cycle regulator expression reveals that KN-93 rather than KN-92 reduced the expression of p53 and p21[2].
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