SG-210
CAS No. : 143162-65-6
(Synonyms: SPR 210)
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| Cat. No. : | HY-106915 |
| M.Wt: | 424.42 |
| Formula: | C18H11F3N2O3S2 |
| Purity: | >98 % |
| Solubility: |
SG-210 (SPR 210) is an orally active and selective aldose reductase (AR) inhibitor. SG-210 has IC50 values of 9.5 nM and 10 nM for AR from porcine lens and human placenta, respectively. SG-210 can inhibit sorbitol accumulation and ameliorate diabetic neuropathy and retinopathy in Streptozotocin (HY-13753)-induced diabetic rats. SG-210 can be used in the research of diseases such as diabetes-related complications[1].
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