Raleukin
CAS No. : 143090-92-0
(Synonyms: Kineret; Anakinra)
| Size | Price | Stock |
|---|---|---|
| 1mg | $140 | In-stock |
| 5mg | $350 | In-stock |
| 10mg | $550 | In-stock |
| 25mg | $1100 | In-stock |
| 50mg | $1650 | In-stock |
| 100mg | $2480 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-108841 |
| M.Wt: | 1000.00 |
| Formula: | C759H1186N208O232S10 |
| Purity: | >98 % |
| Solubility: |
Raleukin (AMG-719) is a recombinant, nonglycosylated human interleukin-1 receptor (IL-1R) antagonist. Raleukin significantly reduces neutrophil accumulation in blood vessels and brain infarct volume as well as improves motor coordination performance in ischemic stroke mice model. Anakinra can be used to study chronic inflammatory disorders like rheumatoid arthritis and cardiovascular recurrence post-myocardial infarction[1][2][3].
IC50 & Target:IL-1R[1].
In Vivo: Combined Etanercept (5 mg/kg, ip) and Anakinra (100 mg/kg, ip. daily for 7 days) substantially improves marginal mass human islet engraftment in immunodeficient mice[2].
Raleukin (AMG-719) enhances tumor growth inhibition in mice receiving peptide vaccination and β-(1-3),(1-6)-D-glucan[3].
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