AKT-IN-6


CAS No. : 1430056-54-4

1430056-54-4
Price and Availability of CAS No. : 1430056-54-4
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5mg $85 In-stock
10mg $140 In-stock
25mg $280 In-stock
50mg $450 In-stock
100mg $720 In-stock
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Cat. No. : HY-19982
M.Wt: 389.43
Formula: C22H20FN5O
Purity: >98 %
Solubility: DMSO : 125 mg/mL (ultrasonic)
Introduction of 1430056-54-4 :

AKT-IN-6 (Example 13) is a potent Akt inhibitor. AKT-IN-6 inhibits Akt1, Akt2 and Akt3 with IC50s < 500nM, respectively. (patent WO2013056015A1). In Vitro: Akt is a central node in cell signaling downstream of growth factors, cytokines, and other cellular stimuli. Aberrant loss or gain of Akt activation underlies the pathophysiological properties of a variety of complex diseases, including type-2 diabetes and cancer[2].

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