| Size | Price | Stock |
|---|---|---|
| 5mg | $690 | In-stock |
| 10mg | $1105 | In-stock |
| 25mg | $2210 | In-stock |
| 50mg | $3320 | In-stock |
| 100mg | $4980 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
| We match the lowest price on market. | ||
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| Cat. No. : | HY-112486 |
| M.Wt: | 641.56 |
| Formula: | C28H25BrN4O5S2 |
| Purity: | >98 % |
| Solubility: | DMSO : 50 mg/mL (ultrasonic;warming;heat to 60°C) |
TA-3166 (Megakaryocytes/platelets inducing agent) is a novel chemically synthesized c-MPL agonist (CMA) and thrombopoietin (TPO) receptor agonist. TA-316 enhances ex vivo platelet generation from human-induced pluripotent stem (iPS) cells[1][2].
In Vitro:TA-316 (0.01-1000 nM; 4 days) stimulates UT-7/TPO and Ba/F3-HuMpl cells proliferation, with the EC50 values of 0.3 and 0.65 nM, respectively[2].
TA-316 (800 nM; 10 days) promotes biased megakaryopoiesis and upregulated MK lineage markers[2].
TA-316 (200 nM; 4 days) preferentially enhances VEGFA and FGF2 expression[2].
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