| Size | Price | Stock |
|---|---|---|
| 1mg | $280 | In-stock |
| 5mg | $670 | In-stock |
| 10mg | $1050 | In-stock |
| 25mg | $1950 | In-stock |
| 50mg | $3000 | In-stock |
| 100 mg | Get quote | |
| 200 mg | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
or Fax: (86)21-58955996
Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-P9919 |
| M.Wt: | 1000.00 |
| Formula: | N/A |
| Purity: | >98 % |
| Solubility: | H2O |
Durvalumab (MEDI 4736) is an human anti-PD-L1 monoclonal antibody[1]. Durvalumab (MEDI4736) completely blocks the binding of PD-L1 to both PD-1 and CD80, with IC50s of 0.1 and 0.04 nM, respectively[2]. IC50 & Target:IC50: 0.1 nM (PD-L1/PD-1), 0.04 nM (PD-L1/CD80)[2] In Vitro:Durvalumab (0.02-20 μg/mL, 3 days) overcomes the inhibitory effect of PD-L1 on T cell activation[1]. In Vivo:Durvalumab (0.1-5 mg/kg, intraperitoneal injection, twice a week, three weeks) suppresses human tumor growth in mouse models through T cell inhibition[1].
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