Usmarapride (free base)
CAS No. : 1428862-32-1
(Synonyms: SUVN-D4010 (free base))
| Size | Price | Stock |
|---|---|---|
| 5mg | $380 | In-stock |
| 10mg | $620 | In-stock |
| 25mg | $1250 | In-stock |
| 50mg | $2000 | In-stock |
| 100mg | $3200 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-116565A |
| M.Wt: | 383.49 |
| Formula: | C21H29N5O2 |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 100 mg/mL |
Usmarapride (SUVN-D4010) free base is a potent, selective, orally active and brain penetrant 5-HT4 receptor partial agonist (EC50=44 nM). Usmarapride (SUVN-D4010) free base can be used for the research of cognitive deficits associated with Alzheimer's disease[1].
In Vivo: Usmarapride (SUVN-D4010) (1-3 mg/kg; p.o.; Male Wistar rats 10-12 weeks old) free base attenuates the long-term memory deficits in object recognition test (ORT)[1].
Usmarapride (1, 3, and 10 mg/kg; p.o.) free base significantly reverses the scopolamine-induced amnesia[1].
Usmarapride free base shows a statistically significant effect at 3.0 mg/kg on both exploration time and recognition index[1].
Usmarapride (SUVN-D4010) free base shows good oral exposures, good bioavailability, and good brain exposures in rats[1].
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