Narirutin


CAS No. : 14259-46-2

14259-46-2
Price and Availability of CAS No. : 14259-46-2
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250mg $532 In-stock
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Cat. No. : HY-N0804
M.Wt: 580.53
Formula: C27H32O14
Purity: >98 %
Solubility: DMSO : 125 mg/mL (ultrasonic)
Introduction of 14259-46-2 :

Narirutin, one of the active constituents isolated from citrus fruits, has antioxidant and anti-inflammatory activities. Narirutin is a shikimate kinase inhibitor with anti-tubercular potency[1][2]. In Vitro:Narirutin (200 μM, 20 h) has no effect on the vitality of RBL-2H3 cells[3].
Narirutin (25 μM, 2.5 h) inhibits β-hex, histamine, IL-4 and TNF-a release were lower than 40% in RBL-2H3 cells. [3].
In Vivo:Narirutin (10 mg/kg, p.o ) reduces eosinophil counts in peripheral blood in OVA-challenged mice[2].
Narirutin (10 mg/kg, p.o ) block the OVA-induced increase in IL-4 but has no effect on the increase in IL-5 [2].

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