Parbendazole
CAS No. : 14255-87-9
(Synonyms: SKF 29044)
| Size | Price | Stock |
|---|---|---|
| 100mg | $52 | In-stock |
| 250mg | $76 | In-stock |
| 1g | $185 | In-stock |
| 5g | $641 | In-stock |
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| Cat. No. : | HY-115364 |
| M.Wt: | 247.29 |
| Formula: | C13H17N3O2 |
| Purity: | >98 % |
| Solubility: | DMSO : 4 mg/mL (ultrasonic) |
Parbendazole is a potent inhibitor of microtubule assembly, destabilizes tubulin, with an EC50 of 530?nM, and exhibits a broad-spectrum anthelmintic activity. IC50 & Target: EC50: 530?nM (tubulin)[1] In Vitro: Parbendazole is a tubulin destabilizer, with an EC50 of 530?nM, and can induce DNA damage[1]. Parbendazole (2-10 μM) inhibits the assembly of microtubules dose-dependently, with an IC50 of 3 μM. Parbendazole (2-20 μM)-treated cells show an complete absence of microtubules in Vero cells[2]. Parbendazole (up to 10 μM) inhibits the growth of CLd-AXE myxamoebae. Parbendazole (2-5 μM) potently inhibits tubulin purified from the wild-type myxamoebae[3].
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