Lobetyolinin


CAS No. : 142451-48-7

142451-48-7
Price and Availability of CAS No. : 142451-48-7
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5mg $350 In-stock
10mg $525 In-stock
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Cat. No. : HY-124031
M.Wt: 558.57
Formula: C26H38O13
Purity: >98 %
Solubility: Ethanol : 6.67 mg/mL (ultrasonic)
Introduction of 142451-48-7 :

Lobetyolinin is a polyacetylene compound. Lobetyolinin can be extracted from the traditional Chinese medicine Codonopsis pilosula. Lobetyolinin has antiarrhythmic effects. Lobetyolinin can be used in liver cancer research[1][2]. In Vitro:Lobetyolinin (50 µM; 24 h) significantly restores the heart rate of larvae and improves atrioventricular block in Terfenadine (HY-B1193)-induced arrhythmia model of Cmlc2-GFP transgenic zebrafish larvae[1].
Lobetyolinin (6 h) restores abnormal heart rate and rhythm in adult zebrafish model[1].
Lobetyolinin (up to 80 µM) shows no significant inhibitory effect on cell viability and does not induce apoptosis in HepG2 and Huh7 hepatocellular carcinoma cell models[2].

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