RN983


CAS No. : 1423129-83-2

1423129-83-2
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Cat. No. : HY-117628
M.Wt: 624.71
Formula: C34H37FN8O3
Purity: >98 %
Solubility:
Introduction of 1423129-83-2 :

RN983 (Compound 1) is a highly selective Bruton's tyrosine kinase (Btk) inhibitor. RN983 inhibits IgG production in B-cells with an IC50 of 2.5 nM and PGD2 production from mast cells with an IC50 of 8.3 nM. RN983 is promising for research of asthma and other allergic diseases[1].

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