Foscenvivint


CAS No. : 1422253-38-0

(Synonyms: PRI-724)

1422253-38-0
Price and Availability of CAS No. : 1422253-38-0
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5mg $100 In-stock
10mg $190 In-stock
25mg $340 In-stock
50mg $540 In-stock
100mg $800 In-stock
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Cat. No. : HY-112045
M.Wt: 658.64
Formula: C33H35N6O7P
Purity: >98 %
Solubility: DMSO : 100 mg/mL (ultrasonic)
Introduction of 1422253-38-0 :

PRI-724 is a selective inhibitor of the CBP/β-catenin interaction. IC50 & Target:CBP/β-catenin[1] In Vivo: PRI-724 is phosphorylated-C-82 and is rapidly hydrolyzed to its active form C-82 in vivo. PRI-724 treatment reduces the fibrosis induced by CCl4 or BDL. C-82, an active form of PRI-724, inhibits the activation of isolated primary mouse quiescent hepatic stellate cells (HSCs) and promotes cell death in culture-activated HSCs[1].

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