Prothionamide (Standard)
CAS No. : 14222-60-7
(Synonyms: Protionamide (Standard))
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| Cat. No. : | HY-B0306R |
| M.Wt: | 180.27 |
| Formula: | C9H12N2S |
| Purity: | >98 % |
| Solubility: |
Prothionamide (Standard) is the analytical standard of Prothionamide (HY-B0306). This product is intended for research and analytical applications. Prothionamide is an orally active thioamide antibacterial agent. Prothionamide is a substrate of OCT1 with a Km value of 805.8 μM. Prothionamide reacts with NAD to form a covalent adduct, with the adduct being a tight-binding inhibitor of Mycobacterium tuberculosis and Mycobacterium leprae InhA. Prothionamide can effectively inhibit the growth of Mycobacterium tuberculosis (MIC = ~0.5 µg/mL) and Mycobacterium leprae. Prothionamide is used in the research of tuberculosis and leprosy[1][2][3][4][5].
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