Hederacoside C
CAS No. : 14216-03-6
(Synonyms: Kalopanaxsaponin B)
| Size | Price | Stock |
|---|---|---|
| 25mg | $60 | In-stock |
| 50mg | $110 | In-stock |
| 100mg | $200 | In-stock |
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| Cat. No. : | HY-N0253 |
| M.Wt: | 1221.38 |
| Formula: | C59H96O26 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
Hederacoside C (Kalopanaxsaponin B) is an ingredient that can be obtained mainly from ivy leaves. Hederacoside C mediates inflammation by inhibiting activation of MAPK/NF-κB and its downstream signaling pathway. Hederacoside C has anti-inflammatory and antibacterial activity[1][2][3].
In Vitro:Hederacoside C (0.1, 1, 10 μM, 1 h) inhibits MAPK/NF-κB and the activation of its downstream signaling pathway in human intestinal epithelial Caco-2 cells to reduce inflammatory response[1].
Hederacoside C (5, 10, 50 μg/mL, 1 h) has anti-inflammatory effects on RAW 264.7 cells stimulated by Staphylococcus aureus[2].
Hederacoside C (5, 10 μg/mL, 2 h) has a protective effect on ECM degradation induced by senescence of mouse chondrocytes[3].
In Vivo:Hederacoside C (0.625, 1.25, 2.5 mg/kg, intraperitoneally injected for 7 consecutive days) can alleviate TNBS-induced enteritis[1].
Hederacoside C (5, 10, 50 mg/kg, intraperitoneally injected for 3 consecutive times for 8 h) can attenuate the breast lesions caused by Staphylococcus aureus[2].
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