WS3
CAS No. : 1421227-52-2
| Size | Price | Stock |
|---|---|---|
| 5mg | $45 | In-stock |
| 10mg | $79 | In-stock |
| 50mg | $250 | In-stock |
| 100mg | $400 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-12462 |
| M.Wt: | 569.58 |
| Formula: | C28H30F3N7O3 |
| Purity: | >98 % |
| Solubility: | DMSO : 2.2 mg/mL (ultrasonic) |
WS3 is a novel proliferative molecule that promotes pancreatic β cell proliferation in rodent and human primary islets. WS3 can be used for the research of type 1 diabetes[1]. IC50 & Target:IC50: 0.28 μM (β cell proliferation)[1] In Vitro: WS3 induces pancreatic R7T1 β cell proliferation in dose response, with an EC50 value of 0.28 μM[1].WS3 (1.0 nM-1.0 μM) reversibly proliferate primary retinal pigment epithelial (RPE) cells isolated from fetal and adult human donors. Following withdrawal of WS3, RPE cells differentiate into a functional monolayer, as exhibited by their expression of mature RPE genes and phagocytosis of photoreceptor outer segments[2].
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