Thiethylperazine
CAS No. : 1420-55-9
| Size | Price | Stock |
|---|---|---|
| 5mg | $99 | In-stock |
| 10mg | $147 | In-stock |
| 25mg | $261 | In-stock |
| 50mg | $390 | In-stock |
| 100mg | $579 | In-stock |
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| Cat. No. : | HY-B1794 |
| M.Wt: | 399.62 |
| Formula: | C22H29N3S2 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
Thiethylperazine, a phenothiazine derivate, is an orally active and potent dopamine D2-receptor and histamine H1-receptor antagonist. Thiethylperazine is also a selective ABCC1activator that reduces amyloid-β (Aβ) load in mice. Thiethylperazine has anti-emetic, antipsychotic and antimicrobial effects[1][2][3]. In Vitro: Thiethylperazine can enhance the antibiotic (Vancomycin) activity at a concentration as low as 2 μg/mL. Thiethylperazine inhibits Vancomycin-sensitive E. faecalis ATCC 29212, Vancomycin-resistant E. faecalis ATCC 51299 and vancomycin-resistant E. faecalis (VREF) isolates with MIC values of 8 μg/mL, 16 μg/mL and 8 μg/mL, respectively[3]. In Vivo: Thiethylperazine (3 mg/kg; intramuscular injection; twice daily; for 30 days) significantly reduces Aβ42 levels in young APP/PS1 mice[2].
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