L-Glutamic acid (monosodium salt)


CAS No. : 142-47-2

142-47-2
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Cat. No. : HY-14608A
M.Wt: 169.11
Formula: C5H8NNaO4
Purity: >98 %
Solubility: H2O : 7.14 mg/mL (ultrasonic);DMSO : < 1 mg/mL
Introduction of 142-47-2 :

L-Glutamic acid monosodium salt is an excitatory amino acid neurotransmitter that acts as an agonist for all subtypes of glutamate receptors (metabolic rhodophylline, NMDA, and AMPA). L-Glutamic acid monosodium salt has an agonist effect on the release of DA from dopaminergic nerve endings. L-Glutamic acid monosodium salt can be used in the study of neurological diseases. L-Glutamic acid monosodium salt acts at ionotropic and metabotropic glutamate receptors[1][2][3][4][5]. In Vitro:L-Glutamic acid monosodium salt (120, 500, 750, 1000 mg/dL) can reduce the harmful effect of lithium on the embryonic development of Xenopus Xenopus[3].
L-Glutamic acid monosodium salt (2, 5, 10, 20 mM, 24-48 h) can induce neuroexcitotoxicity in neuroblastoma[4].
In Vivo:L-Glutamic acid monosodium salt (3 g/kg, subcutaneous injection) can promote excitotoxic degeneration of retinal ganglion cells in mice[1].
L-Glutamic acid monosodium salt (750 mg/kg, intraperitoneal injection) can reduce and inhibit oxidative stress induced by chlorpyrifos (CPF) in rats[5].

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