Miriplatin


CAS No. : 141977-79-9

(Synonyms: SM-11355)

141977-79-9
Price and Availability of CAS No. : 141977-79-9
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Cat. No. : HY-16325A
M.Wt: 764.00
Formula: C34H68N2O4Pt
Purity: >98 %
Solubility: H2O : 0.1 mg/mL (ultrasonic);DMF : 1 mg/mL (ultrasonic);Acetone : 1.1 mg/mL (ultrasonic);chloroform : 43.33 mg/mL (ultrasonic)
Introduction of 141977-79-9 :

Miriplatin (SM-11355) is a chemotherapy agent which belongs to the class of alkylating agents. In Vitro:Miriplatin (SM-11355) suspended in LPD (miriplatin/LPD, 100 μg/mL) inhibits the growth of AH109A cells, forms platinum-DNA adducts, and induces apoptosis[2]. In Vivo:Miriplatin (SM-11355) (0.02-0.4 mg/20 μL) in lipiodol reduces tumor growth rates in a dose dependent manner in rats bearing AH109A tumor cells[1]. Miriplatin/LPD (400 μg/head) significantly reduces the growth of tumor in rats bearing AH109A cells[2].

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