1-N-Boc-3-hydroxyazetidine
CAS No. : 141699-55-0
| Size | Price | Stock |
|---|---|---|
| 10g | $10 | In-stock |
| 25g | $18 | In-stock |
| 100g | $53 | In-stock |
| 500g | $234 | In-stock |
| 1000g | $466 | In-stock |
| > 2 kg | Get quote | |
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| Cat. No. : | HY-40142 |
| M.Wt: | 173.21 |
| Formula: | C8H15NO3 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
1-N-Boc-3-hydroxyazetidine is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). 1-N-Boc-3-hydroxyazetidine is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs
In Vitro: ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2].
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Inquiry Information- Product Name:
- 1-N-Boc-3-hydroxyazetidine
- Cat. No.:
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