LY231617
CAS No. : 141545-89-3
| Size | Price | Stock |
|---|---|---|
| 5mg | $90 | In-stock |
| 10mg | $140 | In-stock |
| 25mg | $290 | In-stock |
| 50mg | $420 | In-stock |
| 100mg | $650 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-103253 |
| M.Wt: | 299.88 |
| Formula: | C17H30ClNO |
| Purity: | >98 % |
| Solubility: | DMSO : 250 mg/mL (ultrasonic) |
LY231617 is a potent and blood-brain barrier penetrable antioxidant. LY231617 is a neuroprotective agent in brain, it can be used for the research of nervous disease[1][2]. In Vitro:LY231617 (0.25, 1, 5, 10, and 25 μM; overnight) attenuates H2O2 toxicity to hippocampal cultures and shows the best effect at a concertration of 10 μM[1]. LY231617 (5 μM; overnight) attenuates 8-isoprostane production and glutathione depletion[1]. In Vivo:LY231617 (50 mg/kg; p.o. 30 minutes before occlusion) reduces global ischemic neuronal injury in rats[2]. LY231617 (20 mg/kg; i.v. 30 minutes after occlusion) protects hippocampus and striatum from four-vessel occlusion[2].
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