LSP4-2022


CAS No. : 1413405-33-0

1413405-33-0
Price and Availability of CAS No. : 1413405-33-0
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5mg $745 In-stock
10mg $1195 In-stock
25mg $2390 In-stock
50mg $3588 In-stock
100mg $5384 In-stock
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Cat. No. : HY-117764
M.Wt: 347.26
Formula: C13H18NO8P
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 1413405-33-0 :

LSP4-2022 is a potent and brain-penetrant mGlu4-selective orthosteric agonist, with an EC50 of 0.11 μM. LSP4-2022 inhibits neurotransmission in cerebellar slices from wild-type but not mGlu4 receptor-knockout mice. LSP4-2022 shows pro-depressant activity[1][2]. IC50 & Target:EC50: 0.11 ± 0.02 μM (mGlu4), 11.6 ± 1.9 μM (mGlu7), 29.2 ± 4.2 μM (mGlu8)[1]

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