PEPA
CAS No. : 141286-78-4
| Size | Price | Stock |
|---|---|---|
| 5mg | $88 | In-stock |
| 10mg | $135 | In-stock |
| 50mg | $530 | In-stock |
| 100mg | $870 | In-stock |
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| 500 mg | Get quote | |
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| Cat. No. : | HY-12509 |
| M.Wt: | 402.44 |
| Formula: | C16H16F2N2O4S2 |
| Purity: | >98 % |
| Solubility: | DMSO : 50 mg/mL (ultrasonic) |
PEPA is an AMPA receptor allosteric potentiator. PEPA shows preferential action of PEPA on the flop form of AMPA receptors. PEPA is a more potent suppressor of desensitization of receptors containing GluR3 and GluR4 as opposed to those containing GluR1. PEPA has antianxiety effects[1][2][3].
In Vitro:PEPA dose-dependently potentiates AMPA-induced increase of [Ca2+]i in rat hippocampal cultures[1].
In Vivo:PEPA (30 mg/kg; i.p.; once) decreases freezing time in a contextual fear freezing paradigm in mice[3].
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